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KMID : 1137020100210010056
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Journal of Gynecologic Oncology
2010 Volume.21 No. 1 p.56 ~ p.58
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Cellular fibroma of the ovary containing Leydig cell hyperplasia: a case report
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Yoon Bo-Sung
Seong Seok-Ju
Park Chong-Taik
Park Hyun
Shim Jeong-Yun
Kim Ji-Young
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Abstract
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Ovarian stromal tumors containing Leydig cell components are rare. Only a few cases of ovarian stromal Leydig cell tumors characterized by clusters of Leydig cells have been reported to date. Here, we present the first case report of a 65-year-old woman with a cellular fibroma of the ovary containing Leydig cell hyperplasia. Microscopic examination revealed the proliferation of spindle cells arranged in intersecting bundles with mild nuclear atypia and an average of 2-3 mitotic figures per ten high-power fields. Multifocal nests of polygonal cells with abundant eosinophilic cytoplasm and round nuclei were seen within the spindle cells. Final pathology of the tumor revealed a cellular fibroma including Leydig cell hyperplasia.
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KEYWORD
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Ovary, Fibroma, Leydig cells
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